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Differentiation and fiber type-specific activity of a muscle creatine kinase intronic enhancer

BACKGROUND: Hundreds of genes, including muscle creatine kinase (MCK), are differentially expressed in fast- and slow-twitch muscle fibers, but the fiber type-specific regulatory mechanisms are not well understood. RESULTS: Modulatory region 1 (MR1) is a 1-kb regulatory region within MCK intron 1 th...

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Detalles Bibliográficos
Autores principales: Tai, Phillip WL, Fisher-Aylor, Katherine I, Himeda, Charis L, Smith, Catherine L, MacKenzie, Alexandra P, Helterline, Deri L, Angello, John C, Welikson, Robert E, Wold, Barbara J, Hauschka, Stephen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157005/
https://www.ncbi.nlm.nih.gov/pubmed/21797989
http://dx.doi.org/10.1186/2044-5040-1-25