Inclusion Body Myositis: Laser Microdissection Reveals Differential Up-Regulation of IFN-γ Signaling Cascade in Attacked versus Nonattacked Myofibers

Sporadic inclusion body myositis (IBM) is a muscle disease with two separate pathogenic components, degeneration and inflammation. Typically, nonnecrotic myofibers are focally surrounded and invaded by CD8(+) T cells and macrophages. Both attacked and nonattacked myofibers express high levels of hum...

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Detalles Bibliográficos
Autores principales: Ivanidze, Jana, Hoffmann, Reinhard, Lochmüller, Hanns, Engel, Andrew G., Hohlfeld, Reinhard, Dornmair, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2011
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157228/
https://www.ncbi.nlm.nih.gov/pubmed/21855683
http://dx.doi.org/10.1016/j.ajpath.2011.05.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157228/
https://www.ncbi.nlm.nih.gov/pubmed/21855683
http://dx.doi.org/10.1016/j.ajpath.2011.05.055

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