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WNT5A Signaling Contributes to Aβ-Induced Neuroinflammation and Neurotoxicity
Neurodegenration is a pathological hallmark of Alzheimer's disease (AD), but the underlying molecular mechanism remains elusive. Here, we present evidence that reveals a crucial role of Wnt5a signaling in this process. We showed that Wnt5a and its receptor Frizzled-5 (Fz5) were up-regulated in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157339/ https://www.ncbi.nlm.nih.gov/pubmed/21857966 http://dx.doi.org/10.1371/journal.pone.0022920 |