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WNT5A Signaling Contributes to Aβ-Induced Neuroinflammation and Neurotoxicity

Neurodegenration is a pathological hallmark of Alzheimer's disease (AD), but the underlying molecular mechanism remains elusive. Here, we present evidence that reveals a crucial role of Wnt5a signaling in this process. We showed that Wnt5a and its receptor Frizzled-5 (Fz5) were up-regulated in...

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Detalles Bibliográficos
Autores principales:	Li, Bei, Zhong, Ling, Yang, Xiangling, Andersson, Tommy, Huang, Min, Tang, Shao-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157339/ https://www.ncbi.nlm.nih.gov/pubmed/21857966 http://dx.doi.org/10.1371/journal.pone.0022920

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