Matrix Metalloproteinase-2 and -9 Secreted by Leukemic Cells Increase the Permeability of Blood-Brain Barrier by Disrupting Tight Junction Proteins

Central nervous system (CNS) involvement remains an important cause of morbidity and mortality in acute leukemia, the mechanisms of leukemic cell infiltration into the CNS have not yet been elucidated. The blood-brain barrier (BBB) makes CNS become a refugee to leukemic cells and serves as a resourc...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Saran, Cen, Jiannong, Huang, Yihong, Shen, Hongjie, Yao, Li, Wang, Yuanyuan, Chen, Zixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157343/
https://www.ncbi.nlm.nih.gov/pubmed/21857898
http://dx.doi.org/10.1371/journal.pone.0020599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157343/
https://www.ncbi.nlm.nih.gov/pubmed/21857898
http://dx.doi.org/10.1371/journal.pone.0020599

Ejemplares similares