Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

BACKGROUND: Sirtuins (SIRT1-7) are a family of NAD-dependent deacetylases and/or ADP-ribosyltransferases that are involved in metabolism, stress responses and longevity. SIRT3 is localized to mitochondria, where it deacetylates and activates a number of enzymes involved in fuel oxidation and energy...

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Detalles Bibliográficos
Autores principales: Finley, Lydia W. S., Haas, Wilhelm, Desquiret-Dumas, Valérie, Wallace, Douglas C., Procaccio, Vincent, Gygi, Steven P., Haigis, Marcia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157345/
https://www.ncbi.nlm.nih.gov/pubmed/21858060
http://dx.doi.org/10.1371/journal.pone.0023295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157345/
https://www.ncbi.nlm.nih.gov/pubmed/21858060
http://dx.doi.org/10.1371/journal.pone.0023295

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