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TIG3 Tumor Suppressor-Dependent Organelle Redistribution and Apoptosis in Skin Cancer Cells

TIG3 is a tumor suppressor protein that limits keratinocyte survival during normal differentiation. It is also important in cancer, as TIG3 level is reduced in tumors and in skin cancer cell lines, suggesting that loss of expression may be required for cancer cell survival. An important goal is iden...

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Detalles Bibliográficos
Autores principales: Scharadin, Tiffany M., Jiang, Haibing, Jans, Ralph, Rorke, Ellen A., Eckert, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157364/
https://www.ncbi.nlm.nih.gov/pubmed/21858038
http://dx.doi.org/10.1371/journal.pone.0023230