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The Kinase Inhibitor SFV785 Dislocates Dengue Virus Envelope Protein from the Replication Complex and Blocks Virus Assembly

Dengue virus (DENV) is the etiologic agent for dengue fever, for which there is no approved vaccine or specific anti-viral drug. As a remedy for this, we explored the use of compounds that interfere with the action of required host factors and describe here the characterization of a kinase inhibitor...

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Detalles Bibliográficos
Autores principales: Anwar, Azlinda, Hosoya, Takamitsu, Leong, Kok Mun, Onogi, Hiroshi, Okuno, Yukiko, Hiramatsu, Toshiyuki, Koyama, Hiroko, Suzuki, Masaaki, Hagiwara, Masatoshi, Garcia-Blanco, Mariano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157368/
https://www.ncbi.nlm.nih.gov/pubmed/21858043
http://dx.doi.org/10.1371/journal.pone.0023246