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The Mitochondrial Genome Is a “Genetic Sanctuary” during the Oncogenic Process

Since Otto Warburg linked mitochondrial physiology and oncogenesis in the 1930s, a number of studies have focused on the analysis of the genetic basis for the presence of aerobic glycolysis in cancer cells. However, little or no evidence exists today to indicate that mtDNA mutations are directly res...

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Detalles Bibliográficos
Autores principales: Seoane, Marcos, Mosquera-Miguel, Ana, Gonzalez, Teresa, Fraga, Maximo, Salas, Antonio, Costoya, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157371/
https://www.ncbi.nlm.nih.gov/pubmed/21858071
http://dx.doi.org/10.1371/journal.pone.0023327