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A Pan-HPV Vaccine Based on Bacteriophage PP7 VLPs Displaying Broadly Cross-Neutralizing Epitopes from the HPV Minor Capsid Protein, L2

BACKGROUND: Current human papillomavirus (HPV) vaccines that are based on virus-like particles (VLPs) of the major capsid protein L1 largely elicit HPV type-specific antibody responses. In contrast, immunization with the HPV minor capsid protein L2 elicits antibodies that are broadly cross-neutraliz...

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Detalles Bibliográficos
Autores principales: Tumban, Ebenezer, Peabody, Julianne, Peabody, David S., Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157372/
https://www.ncbi.nlm.nih.gov/pubmed/21858066
http://dx.doi.org/10.1371/journal.pone.0023310