Probing the Interaction of the Diarylquinoline TMC207 with Its Target Mycobacterial ATP Synthase

Infections with Mycobacterium tuberculosis are substantially increasing on a worldwide scale and new antibiotics are urgently needed to combat concomitantly emerging drug-resistant mycobacterial strains. The diarylquinoline TMC207 is a highly promising drug candidate for treatment of tuberculosis. T...

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Detalles Bibliográficos
Autores principales: Haagsma, Anna C., Podasca, Ioana, Koul, Anil, Andries, Koen, Guillemont, Jerome, Lill, Holger, Bald, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157398/
https://www.ncbi.nlm.nih.gov/pubmed/21858172
http://dx.doi.org/10.1371/journal.pone.0023575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157398/
https://www.ncbi.nlm.nih.gov/pubmed/21858172
http://dx.doi.org/10.1371/journal.pone.0023575

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