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Toll-Like Receptor 2 Induced Angiogenesis and Invasion Is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis

BACKGROUND: Angiogenesis is a critical early event in inflammatory arthritis, facilitating leukocyte migration into the synovium resulting in invasion and destruction of articular cartilage and bone. This study investigates the effect of TLR2 on angiogenesis, EC adhesion and invasion using microvasc...

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Detalles Bibliográficos
Autores principales: Saber, Tajvur, Veale, Douglas J., Balogh, Emese, McCormick, Jennifer, NicAnUltaigh, Sinead, Connolly, Mary, Fearon, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157402/
https://www.ncbi.nlm.nih.gov/pubmed/21858161
http://dx.doi.org/10.1371/journal.pone.0023540