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Toll-Like Receptor 2 Induced Angiogenesis and Invasion Is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis
BACKGROUND: Angiogenesis is a critical early event in inflammatory arthritis, facilitating leukocyte migration into the synovium resulting in invasion and destruction of articular cartilage and bone. This study investigates the effect of TLR2 on angiogenesis, EC adhesion and invasion using microvasc...
Autores principales: | Saber, Tajvur, Veale, Douglas J., Balogh, Emese, McCormick, Jennifer, NicAnUltaigh, Sinead, Connolly, Mary, Fearon, Ursula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157402/ https://www.ncbi.nlm.nih.gov/pubmed/21858161 http://dx.doi.org/10.1371/journal.pone.0023540 |
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