Lipopolysaccharide and Tumor Necrosis Factor Regulate Parkin Expression via Nuclear Factor-Kappa B

Inflammation and oxidative stress have been implicated in the pathophysiology of Parkinson's disease (PD) and inhibition of microglial activation attenuates degeneration of dopaminergic (DA) neurons in animal models of PD. Loss-of-function mutations in the parkin gene, which encodes an E3 ubiqu...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Thi A., Nguyen, Andrew D., Chang, Jianjun, Goldberg, Matthew S., Lee, Jae-Kyung, Tansey, Malú G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157435/
https://www.ncbi.nlm.nih.gov/pubmed/21858193
http://dx.doi.org/10.1371/journal.pone.0023660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157435/
https://www.ncbi.nlm.nih.gov/pubmed/21858193
http://dx.doi.org/10.1371/journal.pone.0023660

Ejemplares similares