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Streptozotocin-Induced Early Thermal Hyperalgesia is independent of Glycemic State of Rats: Role of Transient Receptor Potential Vanilloid 1(TRPV1) and Inflammatory mediators

BACKGROUND: Streptozotocin (STZ) is used as a common tool to induce diabetes and to study diabetes-induced complications including diabetic peripheral neuropathy (DPN). Previously, we have reported that STZ induces a direct effect on neurons through expression and function of the Transient receptor...

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Detalles Bibliográficos
Autores principales: Bishnoi, Mahendra, Bosgraaf, Christine A, Abooj, Mruvil, Zhong, Linlin, Premkumar, Louis S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157448/
https://www.ncbi.nlm.nih.gov/pubmed/21794120
http://dx.doi.org/10.1186/1744-8069-7-52