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One-Step Preservation of Phosphoproteins and Tissue Morphology at Room Temperature for Diagnostic and Research Specimens
BACKGROUND: There is an urgent need to measure phosphorylated cell signaling proteins in cancer tissue for the individualization of molecular targeted kinase inhibitor therapy. However, phosphoproteins fluctuate rapidly following tissue procurement. Snap-freezing preserves phosphoproteins, but is un...
Autores principales: | Mueller, Claudius, Edmiston, Kirsten H., Carpenter, Calvin, Gaffney, Eoin, Ryan, Ciara, Ward, Ronan, White, Susan, Memeo, Lorenzo, Colarossi, Cristina, Petricoin, Emanuel F., Liotta, Lance A., Espina, Virginia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157466/ https://www.ncbi.nlm.nih.gov/pubmed/21858221 http://dx.doi.org/10.1371/journal.pone.0023780 |
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