The Hepatitis C Virus E1 Glycoprotein Undergoes Productive Folding but Accelerated Degradation When Expressed as an Individual Subunit in CHO Cells

Hepatitis C Virus E1E2 heterodimers are components of the viral spike. Although there is a general agreement on the necessity of the co-expression of both E1 and E2 on a single coding unit for their productive folding and assembly, in a previous study using an in vitro system we obtained strong indi...

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Detalles Bibliográficos
Autores principales: Botti, Valentina, Bianchi, Alessia, Foung, Steven K. H., Merola, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157478/
https://www.ncbi.nlm.nih.gov/pubmed/21858229
http://dx.doi.org/10.1371/journal.pone.0023838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157478/
https://www.ncbi.nlm.nih.gov/pubmed/21858229
http://dx.doi.org/10.1371/journal.pone.0023838

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