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Huprines as a new family of dual acting trypanocidal–antiplasmodial agents

A series of 19 huprines has been evaluated for their activity against cultured bloodstream forms of Trypanosoma brucei and Plasmodium falciparum. Moreover, cytotoxicity against rat myoblast L6 cells was assessed for selected huprines. All the tested huprines are moderately potent and selective trypa...

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Detalles Bibliográficos
Autores principales: Defaux, Julien, Sala, Marta, Formosa, Xavier, Galdeano, Carles, Taylor, Martin C., Alobaid, Waleed A.A., Kelly, John M., Wright, Colin W., Camps, Pelayo, Muñoz-Torrero, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157558/
https://www.ncbi.nlm.nih.gov/pubmed/21315611
http://dx.doi.org/10.1016/j.bmc.2011.01.028