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Huprines as a new family of dual acting trypanocidal–antiplasmodial agents
A series of 19 huprines has been evaluated for their activity against cultured bloodstream forms of Trypanosoma brucei and Plasmodium falciparum. Moreover, cytotoxicity against rat myoblast L6 cells was assessed for selected huprines. All the tested huprines are moderately potent and selective trypa...
Autores principales: | Defaux, Julien, Sala, Marta, Formosa, Xavier, Galdeano, Carles, Taylor, Martin C., Alobaid, Waleed A.A., Kelly, John M., Wright, Colin W., Camps, Pelayo, Muñoz-Torrero, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157558/ https://www.ncbi.nlm.nih.gov/pubmed/21315611 http://dx.doi.org/10.1016/j.bmc.2011.01.028 |
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