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Promise and pitfalls of the Immunochip

Genomewide association studies (GWAS) have proven a powerful hypothesis-free method to identify common disease-associated variants. Even quite large GWAS, however, have only at best identified moderate proportions of the genetic variants contributing to disease heritability. To provide cost-effectiv...

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Detalles Bibliográficos
Autores principales: Cortes, Adrian, Brown, Matthew A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157635/
https://www.ncbi.nlm.nih.gov/pubmed/21345260
http://dx.doi.org/10.1186/ar3204