Ongoing GC-Biased Evolution Is Widespread in the Human Genome and Enriched Near Recombination Hot Spots

Fast evolving regions of many metazoan genomes show a bias toward substitutions that change weak (A,T) into strong (G,C) base pairs. Single-nucleotide polymorphisms (SNPs) do not share this pattern, suggesting that it results from biased fixation rather than biased mutation. Supporting this hypothes...

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Detalles Bibliográficos
Autores principales: Katzman, Sol, Capra, John A., Haussler, David, Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157837/
https://www.ncbi.nlm.nih.gov/pubmed/21697099
http://dx.doi.org/10.1093/gbe/evr058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157837/
https://www.ncbi.nlm.nih.gov/pubmed/21697099
http://dx.doi.org/10.1093/gbe/evr058

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