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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
The number of significant genetic associations with common complex traits is constantly increasing. However, most of these associations have not been understood at molecular level. One of the mechanisms mediating the effect of DNA variants on phenotypes is gene expression, which has been shown to be...
Autores principales: | Paracchini, Silvia, Monaco, Anthony P., Knight, Julian C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157858/ https://www.ncbi.nlm.nih.gov/pubmed/21085102 http://dx.doi.org/10.3791/2279 |
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