Natural Splice Variant of MHC Class I Cytoplasmic Tail Enhances Dendritic Cell-Induced CD8(+) T-Cell Responses and Boosts Anti-Tumor Immunity

Dendritic cell (DC)-mediated presentation of MHC class I (MHC-I)/peptide complexes is a crucial first step in the priming of CTL responses, and the cytoplasmic tail of MHC-I plays an important role in modulating this process. Several species express a splice variant of the MHC-I tail that deletes ex...

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Detalles Bibliográficos
Autores principales: Rodríguez-Cruz, Tania G., Liu, Shujuan, Khalili, Jahan S., Whittington, Mayra, Zhang, Minying, Overwijk, Willem, Lizée, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157908/
https://www.ncbi.nlm.nih.gov/pubmed/21860662
http://dx.doi.org/10.1371/journal.pone.0022939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157908/
https://www.ncbi.nlm.nih.gov/pubmed/21860662
http://dx.doi.org/10.1371/journal.pone.0022939

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