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Natural Splice Variant of MHC Class I Cytoplasmic Tail Enhances Dendritic Cell-Induced CD8(+) T-Cell Responses and Boosts Anti-Tumor Immunity
Dendritic cell (DC)-mediated presentation of MHC class I (MHC-I)/peptide complexes is a crucial first step in the priming of CTL responses, and the cytoplasmic tail of MHC-I plays an important role in modulating this process. Several species express a splice variant of the MHC-I tail that deletes ex...
Autores principales: | Rodríguez-Cruz, Tania G., Liu, Shujuan, Khalili, Jahan S., Whittington, Mayra, Zhang, Minying, Overwijk, Willem, Lizée, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157908/ https://www.ncbi.nlm.nih.gov/pubmed/21860662 http://dx.doi.org/10.1371/journal.pone.0022939 |
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