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Frequent Beneficial Mutations during Single-Colony Serial Transfer of Streptococcus pneumoniae
The appearance of new mutations within a population provides the raw material for evolution. The consistent decline in fitness observed in classical mutation accumulation studies has provided support for the long-held view that deleterious mutations are more common than beneficial mutations. Here we...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158050/ https://www.ncbi.nlm.nih.gov/pubmed/21876679 http://dx.doi.org/10.1371/journal.pgen.1002232 |