BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice

The deafness locus DFNB1 contains GJB2, the gene encoding connexin26 and GJB6, encoding connexin30, which appear to be coordinately regulated in the inner ear. In this work, we investigated the expression and function of connexin26 and connexin30 from postnatal day 5 to adult age in double transgeni...

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Detalles Bibliográficos
Autores principales: Crispino, Giulia, Di Pasquale, Giovanni, Scimemi, Pietro, Rodriguez, Laura, Galindo Ramirez, Fabian, De Siati, Romolo Daniele, Santarelli, Rosa Maria, Arslan, Edoardo, Bortolozzi, Mario, Chiorini, John A., Mammano, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158073/
https://www.ncbi.nlm.nih.gov/pubmed/21876744
http://dx.doi.org/10.1371/journal.pone.0023279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158073/
https://www.ncbi.nlm.nih.gov/pubmed/21876744
http://dx.doi.org/10.1371/journal.pone.0023279

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