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Meraculous: De Novo Genome Assembly with Short Paired-End Reads

We describe a new algorithm, meraculous, for whole genome assembly of deep paired-end short reads, and apply it to the assembly of a dataset of paired 75-bp Illumina reads derived from the 15.4 megabase genome of the haploid yeast Pichia stipitis. More than 95% of the genome is recovered, with no er...

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Detalles Bibliográficos
Autores principales: Chapman, Jarrod A., Ho, Isaac, Sunkara, Sirisha, Luo, Shujun, Schroth, Gary P., Rokhsar, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158087/
https://www.ncbi.nlm.nih.gov/pubmed/21876754
http://dx.doi.org/10.1371/journal.pone.0023501