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Hyperthermia Induces the ER Stress Pathway

BACKGROUND: The ER chaperone GRP78/BiP is a homolog of the Hsp70 family of heat shock proteins, yet GRP78/BiP is not induced by heat shock but instead by ER stress. However, previous studies had not considered more physiologically relevant temperature elevation associated with febrile hyperthermia....

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Detalles Bibliográficos
Autores principales: Xu, Xu, Gupta, Sounak, Hu, Wenli, McGrath, Barbara C., Cavener, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158104/
https://www.ncbi.nlm.nih.gov/pubmed/21876766
http://dx.doi.org/10.1371/journal.pone.0023740