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Hyperthermia Induces the ER Stress Pathway
BACKGROUND: The ER chaperone GRP78/BiP is a homolog of the Hsp70 family of heat shock proteins, yet GRP78/BiP is not induced by heat shock but instead by ER stress. However, previous studies had not considered more physiologically relevant temperature elevation associated with febrile hyperthermia....
Autores principales: | Xu, Xu, Gupta, Sounak, Hu, Wenli, McGrath, Barbara C., Cavener, Douglas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158104/ https://www.ncbi.nlm.nih.gov/pubmed/21876766 http://dx.doi.org/10.1371/journal.pone.0023740 |
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