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Synthesis and crystal structures of 5'-phenylspiro[indoline-3, 2'-pyrrolidin]-2-one derivatives

BACKGROUND: The spiro- indole-pyrrolidine ring system is a frequently encountered structural motif in many biologically important and pharmacologically relevant alkaloids. The derivatives of spirooxindole ring systems are used as antimicrobial, antitumour agents and as inhibitors of the human NKI re...

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Detalles Bibliográficos
Autores principales: Sundar, Jeyaperumal Kalyana, Rajesh, Stephen Michael, Sivamani, Jeyaraman, Perumal, Subbu, Natarajan, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158111/
https://www.ncbi.nlm.nih.gov/pubmed/21791053
http://dx.doi.org/10.1186/1752-153X-5-45