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Molecular characterization of the Corynebacterium pseudotuberculosis hsp60-hsp10 operon, and evaluation of the immune response and protective efficacy induced by hsp60 DNA vaccination in mice

BACKGROUND: Heat shock proteins (HSPs) are important candidates for the development of vaccines because they are usually able to promote both humoral and cellular immune responses in mammals. We identified and characterized the hsp60-hsp10 bicistronic operon of the animal pathogen Corynebacterium ps...

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Detalles Bibliográficos
Autores principales: Costa, Marcilia P, McCulloch, John A, Almeida, Síntia S, Dorella, Fernanda A, Fonseca, Cristina T, Oliveira, Diana M, Teixeira, Maria FS, Laskowska, Ewa, Lipinska, Barbara, Meyer, Roberto, Portela, Ricardo W, Oliveira, Sérgio C, Miyoshi, Anderson, Azevedo, Vasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158118/
https://www.ncbi.nlm.nih.gov/pubmed/21774825
http://dx.doi.org/10.1186/1756-0500-4-243