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Molecular characterization of the Corynebacterium pseudotuberculosis hsp60-hsp10 operon, and evaluation of the immune response and protective efficacy induced by hsp60 DNA vaccination in mice
BACKGROUND: Heat shock proteins (HSPs) are important candidates for the development of vaccines because they are usually able to promote both humoral and cellular immune responses in mammals. We identified and characterized the hsp60-hsp10 bicistronic operon of the animal pathogen Corynebacterium ps...
Autores principales: | Costa, Marcilia P, McCulloch, John A, Almeida, Síntia S, Dorella, Fernanda A, Fonseca, Cristina T, Oliveira, Diana M, Teixeira, Maria FS, Laskowska, Ewa, Lipinska, Barbara, Meyer, Roberto, Portela, Ricardo W, Oliveira, Sérgio C, Miyoshi, Anderson, Azevedo, Vasco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158118/ https://www.ncbi.nlm.nih.gov/pubmed/21774825 http://dx.doi.org/10.1186/1756-0500-4-243 |
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