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S-Nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats

BACKGROUND: Traumatic brain injury (TBI) induces primary and secondary damage in both the endothelium and the brain parenchyma, collectively termed the neurovascular unit. While neurons die quickly by necrosis, a vicious cycle of secondary injury in endothelial cells exacerbates the initial injury i...

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Detalles Bibliográficos
Autores principales: Khan, Mushfiquddin, Sakakima, Harutoshi, Dhammu, Tajinder S, Shunmugavel, Anandakumar, Im, Yeong-Bin, Gilg, Anne G, Singh, Avtar K, Singh, Inderjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158546/
https://www.ncbi.nlm.nih.gov/pubmed/21733162
http://dx.doi.org/10.1186/1742-2094-8-78