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Quantitative characterization and analysis of the dynamic NF-κB response in microglia

BACKGROUND: Activation of the NF-κB transcription factor and its associated gene expression in microglia is a key component in the response to brain injury. Its activation is dynamic and is part of a network of biochemical species with multiple feedback regulatory mechanisms. Mathematical modeling,...

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Detalles Bibliográficos
Autores principales: Sheppard, Patrick W, Sun, Xiaoyun, Emery, John F, Giffard, Rona G, Khammash, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158563/
https://www.ncbi.nlm.nih.gov/pubmed/21729324
http://dx.doi.org/10.1186/1471-2105-12-276