Cargando…

Quantitative characterization and analysis of the dynamic NF-κB response in microglia

BACKGROUND: Activation of the NF-κB transcription factor and its associated gene expression in microglia is a key component in the response to brain injury. Its activation is dynamic and is part of a network of biochemical species with multiple feedback regulatory mechanisms. Mathematical modeling,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheppard, Patrick W, Sun, Xiaoyun, Emery, John F, Giffard, Rona G, Khammash, Mustafa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158563/ https://www.ncbi.nlm.nih.gov/pubmed/21729324 http://dx.doi.org/10.1186/1471-2105-12-276

Ejemplares similares

Overexpression of Heat Shock Protein 72 Attenuates NF-κB Activation Using a Combination of Regulatory Mechanisms in Microglia
por: Sheppard, Patrick W., et al.
Publicado: (2014)

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways
por: Kacimi, Rachid, et al.
Publicado: (2011)

Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway
por: Jie, Zuliang, et al.
Publicado: (2021)

Corticosterone Preexposure Increases NF-κB Translocation and Sensitizes IL-1β Responses in BV2 Microglia-Like Cells
por: Liu, JiaJun, et al.
Publicado: (2018)

Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-κB Pathway in Microglia Cells
por: Zhu, Cansheng, et al.
Publicado: (2012)

The Interplay between Cyclic AMP, MAPK, and NF-κB Pathways in Response to Proinflammatory Signals in Microglia
por: Ghosh, Mousumi, et al.
Publicado: (2015)

Candesartan modulates microglia activation and polarization via NF-κB signaling pathway
por: Qie, Shuyan, et al.
Publicado: (2020)

Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF-κB Signaling
por: Hou, Yuanyuan, et al.
Publicado: (2021)

Brazilian Green Propolis Suppresses the Hypoxia-Induced Neuroinflammatory Responses by Inhibiting NF-κB Activation in Microglia
por: Wu, Zhou, et al.
Publicado: (2013)

TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway
por: Huang, Ji-Cheng, et al.
Publicado: (2022)

Nitrosporeusine analogue ameliorates Chandipura virus induced inflammatory response in CNS via NFκb inactivation in microglia
por: Verma, Abhishek Kumar, et al.
Publicado: (2018)

TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF‐κB signaling
por: Li, Caixia, et al.
Publicado: (2018)

Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia
por: Aslanidis, Alexander, et al.
Publicado: (2015)

Tabersonine Inhibits the Lipopolysaccharide-Induced Neuroinflammatory Response in BV2 Microglia Cells via the NF-κB Signaling Pathway
por: Shi, Jiaotai, et al.
Publicado: (2022)

The role of LRRK2 on PKA-NFκB pathway in microglia cells: implications for Parkinson’s disease
por: Russo, Isabella
Publicado: (2019)

Electroacupuncture Attenuates Inflammation after Ischemic Stroke by Inhibiting NF-κB-Mediated Activation of Microglia
por: Liu, Rong, et al.
Publicado: (2020)

Sodium aescinate inhibits microglia activation through NF-κB pathway and exerts neuroprotective effect
por: Xu, Fei, et al.
Publicado: (2023)

NF-κB pathway controls mitochondrial dynamics
por: Laforge, M, et al.
Publicado: (2016)

Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia
por: Li, Baojing, et al.
Publicado: (2022)

NF-κB regulation: the nuclear response
por: Mankan, Arun K, et al.
Publicado: (2009)

Prophylactic inhibition of NF-κB expression in microglia leads to attenuation of hypoxic ischemic injury of the immature brain
por: Zaghloul, Nahla, et al.
Publicado: (2020)

Single-Cell and Population NF-κB Dynamic Responses Depend on Lipopolysaccharide Preparation
por: Gutschow, Miriam V., et al.
Publicado: (2013)

Gualou Guizhi Granule Suppresses LPS-Induced Inflammatory Response of Microglia and Protects against Microglia-Mediated Neurotoxicity in HT-22 via Akt/NF-κB Signaling Pathways
por: Chang, Xiaona, et al.
Publicado: (2021)

Tetrathiomolybdate Treatment Leads to the Suppression of Inflammatory Responses through the TRAF6/NFκB Pathway in LPS-Stimulated BV-2 Microglia
por: Wang, Zhuo, et al.
Publicado: (2018)

NF‐κB and HIF crosstalk in immune responses
por: D'Ignazio, Laura, et al.
Publicado: (2015)

The NF-κB Nucleolar Stress Response Pathway
por: Thoms, Hazel C., et al.
Publicado: (2021)

Fluoxetine suppresses inflammatory reaction in microglia under OGD/R challenge via modulation of NF-κB signaling
por: Tian, Mouli, et al.
Publicado: (2019)

Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF-κB signaling in microglia
por: Madhi, Iskander, et al.
Publicado: (2021)

Exposure of Microglia to Interleukin-4 Represses NF-κB-Dependent Transcription of Toll-Like Receptor-Induced Cytokines
por: Zuiderwijk-Sick, Ella A., et al.
Publicado: (2021)

Ferulic acid alleviates retinal neovascularization by modulating microglia/macrophage polarization through the ROS/NF-κB axis
por: Sun, Xiaowei, et al.
Publicado: (2022)

Dynamic Regulation of NF-κB Response in Innate Immunity: The Case of the IMD Pathway in Drosophila
por: Cammarata-Mouchtouris, Alexandre, et al.
Publicado: (2022)

Astrocyte Proliferation Following Stroke in the Mouse Depends on Distance from the Infarct
por: Barreto, George E., et al.
Publicado: (2011)

NF-κB and Disease
por: Poma, Paola
Publicado: (2020)

NF-κB Members Left Home: NF-κB-Independent Roles in Cancer
por: Colomer, Carlota, et al.
Publicado: (2017)

MicroRNAs Modulate the Dynamics of the NF-κB Signaling Pathway
por: Vaz, Candida, et al.
Publicado: (2011)

Quantitative imaging assay for NF-κB nuclear translocation in primary human macrophages
por: Noursadeghi, Mahdad, et al.
Publicado: (2008)

NF-κB, the Importance of Being Dynamic: Role and Insights in Cancer
por: Colombo, Federica, et al.
Publicado: (2018)

NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration
por: Dorrington, Michael G., et al.
Publicado: (2019)

High-Throughput Analysis of NF-κB Dynamics in Single Cells Reveals Basal Nuclear Localization of NF-κB and Spontaneous Activation of Oscillations
por: Zambrano, Samuel, et al.
Publicado: (2014)

Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro
por: Yao, Linli, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_45dv3dqdebhtd33e1h1j3b3nbi