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Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL

BACKGROUND: At the beginning of neurogenesis, massive brain cell death occurs and more than 50% of cells are eliminated by apoptosis along with neuronal differentiation. However, few studies were conducted so far regarding the regulation of neural progenitor cells (NPCs) death during development. Be...

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Detalles Bibliográficos
Autores principales: Go, Hyo Sang, Seo, Jung Eun, Kim, Ki Chan, Han, So Min, Kim, Pitna, Kang, Young Sun, Han, Seol Heui, Shin, Chan Young, Ko, Kwang Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158748/
https://www.ncbi.nlm.nih.gov/pubmed/21722408
http://dx.doi.org/10.1186/1423-0127-18-48