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The Depolarizing Action of GABA in Cultured Hippocampal Neurons Is Not Due to the Absence of Ketone Bodies

Two recent reports propose that the depolarizing action of GABA in the immature brain is an artifact of in vitro preparations in which glucose is the only energy source. The authors argue that this does not mimic the physiological environment because the suckling rats use ketone bodies and pyruvate...

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Detalles Bibliográficos
Autores principales: Waddell, Jaylyn, Kim, Jimok, Alger, Bradley E., McCarthy, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158756/
https://www.ncbi.nlm.nih.gov/pubmed/21886776
http://dx.doi.org/10.1371/journal.pone.0023020