APC(cdh1) Mediates Degradation of the Oncogenic Rho-GEF Ect2 after Mitosis

BACKGROUND: Besides regulation of actin cytoskeleton-dependent functions, Rho GTPase pathways are essential to cell cycle progression and cell division. Rho, Rac and Cdc42 regulate G1 to S phase progression and are involved in cytokinesis. RhoA GDP/GTP cycling is required for normal cytokinesis and...

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Detalles Bibliográficos
Autores principales: Liot, Caroline, Seguin, Laetitia, Siret, Aurélie, Crouin, Catherine, Schmidt, Susanne, Bertoglio, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158779/
https://www.ncbi.nlm.nih.gov/pubmed/21886810
http://dx.doi.org/10.1371/journal.pone.0023676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158779/
https://www.ncbi.nlm.nih.gov/pubmed/21886810
http://dx.doi.org/10.1371/journal.pone.0023676

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