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APC(cdh1) Mediates Degradation of the Oncogenic Rho-GEF Ect2 after Mitosis
BACKGROUND: Besides regulation of actin cytoskeleton-dependent functions, Rho GTPase pathways are essential to cell cycle progression and cell division. Rho, Rac and Cdc42 regulate G1 to S phase progression and are involved in cytokinesis. RhoA GDP/GTP cycling is required for normal cytokinesis and...
Autores principales: | Liot, Caroline, Seguin, Laetitia, Siret, Aurélie, Crouin, Catherine, Schmidt, Susanne, Bertoglio, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158779/ https://www.ncbi.nlm.nih.gov/pubmed/21886810 http://dx.doi.org/10.1371/journal.pone.0023676 |
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