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Sex-Specific Dynamics of Global Chromatin Changes in Fetal Mouse Germ Cells

Mammalian germ cells undergo global reprogramming of DNA methylation during their development. Global DNA demethylation occurs around the time when the primordial germ cells colonize the embryonic gonads and this coincides with dynamic changes in chromatin composition. Global de novo DNA methylation...

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Detalles Bibliográficos
Autores principales: Abe, Masanobu, Tsai, Shirley Y., Jin, Seung-Gi, Pfeifer, Gerd P., Szabó, Piroska E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158789/
https://www.ncbi.nlm.nih.gov/pubmed/21886830
http://dx.doi.org/10.1371/journal.pone.0023848