IFN-γ Triggered STAT1-PKB/AKT Signalling Pathway Influences the Function of Alloantigen Reactive Regulatory T Cells

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) play a key role in the induction and maintenance of peripheral tolerance. Rapid and transient production of IFN-γ by Tregs from mice tolerized to alloantigen in vivo has been shown to be critical for their regulatory function. This IFN-γ has the poten...

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Detalles Bibliográficos
Autores principales: Wei, B, Baker, S, Wieckiewicz, J, Wood, K J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2010
Materias:
Laboratory Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158990/
https://www.ncbi.nlm.nih.gov/pubmed/19889125
http://dx.doi.org/10.1111/j.1600-6143.2009.02858.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158990/
https://www.ncbi.nlm.nih.gov/pubmed/19889125
http://dx.doi.org/10.1111/j.1600-6143.2009.02858.x

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