Cargando…
IFN-γ Triggered STAT1-PKB/AKT Signalling Pathway Influences the Function of Alloantigen Reactive Regulatory T Cells
CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) play a key role in the induction and maintenance of peripheral tolerance. Rapid and transient production of IFN-γ by Tregs from mice tolerized to alloantigen in vivo has been shown to be critical for their regulatory function. This IFN-γ has the poten...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Inc
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158990/ https://www.ncbi.nlm.nih.gov/pubmed/19889125 http://dx.doi.org/10.1111/j.1600-6143.2009.02858.x |