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TP53 Mutations and HBX Status Analysis in Hepatocellular Carcinomas from Iran: Evidence for Lack of Association between HBV Genotype D and TP53 R249S Mutations

High incidence of HCC is mostly due to the combination of two major risk factors, chronic infection with hepatitis B (HBV) and/or C (HCV) viruses and exposure to the mycotoxin aflatoxin B(1), which induces a particular mutation at codon 249 in TP53 (R249S). Eight genotypes of HBV are diversely found...

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Detalles Bibliográficos
Autores principales: Abedi-Ardekani, Behnoush, Gouas, Doriane, Villar, Stephanie, Sotoudeh, Masoud, Hainaut, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159019/
https://www.ncbi.nlm.nih.gov/pubmed/21869931
http://dx.doi.org/10.1155/2011/475965