Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKBα/AKT and Induces Apoptosis

We identified a major peptide signaling target of EGF/EGFR pathway and explored the consequences of blocking or activating this pathway in the first trimester extravillous trophoblast cells, HTR-8/SVneo. A global analysis of protein phosphorylation was undertaken using novel technology (Kinexus Kine...

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Detalles Bibliográficos
Autores principales: Bolnick, J., Albitar, L., Laidler, L. L., Abdullah, R., Leslie, K. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159379/
https://www.ncbi.nlm.nih.gov/pubmed/21876698
http://dx.doi.org/10.1155/2011/896896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159379/
https://www.ncbi.nlm.nih.gov/pubmed/21876698
http://dx.doi.org/10.1155/2011/896896

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