TRIM5 Acts as More Than a Retroviral Restriction Factor

The retrovirus restriction factor TRIM5α blocks post-entry infection of retroviruses in a species-specific manner. As a cellular E3 ubiquitin ligase, TRIM5α binds to the retroviral capsid lattice in the cytoplasm of an infected cell and accelerates the uncoating process of retroviral capsid, thus pr...

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Detalles Bibliográficos
Autores principales: de Silva, Suresh, Wu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159411/
https://www.ncbi.nlm.nih.gov/pubmed/21866272
http://dx.doi.org/10.3390/v3071204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159411/
https://www.ncbi.nlm.nih.gov/pubmed/21866272
http://dx.doi.org/10.3390/v3071204

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