Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence

RET protein functions as a receptor-type tyrosine kinase and has been found to be aberrantly expressed in a wide range of human diseases. A highly GC-rich region upstream of the promoter plays an important role in the transcriptional regulation of RET. Here, we report the NMR solution structure of t...

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Detalles Bibliográficos
Autores principales: Tong, Xiaotian, Lan, Wenxian, Zhang, Xu, Wu, Houming, Liu, Maili, Cao, Chunyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159441/
https://www.ncbi.nlm.nih.gov/pubmed/21540209
http://dx.doi.org/10.1093/nar/gkr233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159441/
https://www.ncbi.nlm.nih.gov/pubmed/21540209
http://dx.doi.org/10.1093/nar/gkr233

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