The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks

Type II DNA topoisomerases (topos) catalyse changes in DNA topology by passing one double-stranded DNA segment through another. This reaction is essential to processes such as replication and transcription, but carries with it the inherent danger of permanent double-strand break (DSB) formation. All...

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Detalles Bibliográficos
Autores principales: Bates, Andrew D., Berger, James M., Maxwell, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159449/
https://www.ncbi.nlm.nih.gov/pubmed/21525132
http://dx.doi.org/10.1093/nar/gkr258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159449/
https://www.ncbi.nlm.nih.gov/pubmed/21525132
http://dx.doi.org/10.1093/nar/gkr258

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