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Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence

The epigenetic code of DNA methylation is interpreted chiefly by methyl cytosine binding domain (MBD) proteins which in turn recruit multiprotein co-repressor complexes. We previously isolated one such complex, MBD2-NuRD, from primary erythroid cells and have shown it contributes to embryonic/fetal...

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Detalles Bibliográficos
Autores principales: Scarsdale, J. Neel, Webb, Heather D., Ginder, Gordon D., Williams, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159451/
https://www.ncbi.nlm.nih.gov/pubmed/21531701
http://dx.doi.org/10.1093/nar/gkr262