Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1

The ETS (E26) protein Elk-1 serves as a paradigm for mitogen-responsive transcription factors. It is multiply phosphorylated by mitogen-activated protein kinases (MAPKs), which it recruits into pre-initiation complexes on target gene promoters. However, events preparatory to Elk-1 phosphorylation ar...

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Detalles Bibliográficos
Autores principales: Evans, Emma L., Saxton, Janice, Shelton, Samuel J., Begitt, Andreas, Holliday, Nicholas D., Hipskind, Robert A., Shaw, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159454/
https://www.ncbi.nlm.nih.gov/pubmed/21543455
http://dx.doi.org/10.1093/nar/gkr266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159454/
https://www.ncbi.nlm.nih.gov/pubmed/21543455
http://dx.doi.org/10.1093/nar/gkr266

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