Characterization of DNA with an 8-oxoguanine modification

The oxidation of DNA resulting from reactive oxygen species generated during aerobic respiration is a major cause of genetic damage that, if not repaired, can lead to mutations and potentially an increase in the incidence of cancer and aging. A major oxidation product generated in cells is 8-oxoguan...

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Detalles Bibliográficos
Autores principales: Singh, Sreelekha K., Szulik, Marta W., Ganguly, Manjori, Khutsishvili, Irine, Stone, Michael P., Marky, Luis A., Gold, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159457/
https://www.ncbi.nlm.nih.gov/pubmed/21572101
http://dx.doi.org/10.1093/nar/gkr275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159457/
https://www.ncbi.nlm.nih.gov/pubmed/21572101
http://dx.doi.org/10.1093/nar/gkr275

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